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Galactose metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
melibiose + H2O <=> D-galactose + D-glucose 3.2.1.22 alpha-galactosidase
3.2.1.28 alpha,alpha-trehalase


D-galactose + NADP+ <=> D-galactono-1,4-lactone + NADPH + H+ 1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase




monogalactosylglycerol + H2O <=> D-galactose + glycerol 3.2.1.22 alpha-galactosidase

2-dehydro-3-deoxy-D-galactonate_6-phosphate <=> D-glyceraldehyde_3-phosphate + pyruvate 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase
4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase



2-dehydro-3-deoxy-D-galactonate + ATP <=> H+ + 2-dehydro-3-deoxy-D-galactonate_6-phosphate + ADP 2.7.1.178 2-dehydro-3-deoxyglucono/galactono-kinase
2.7.1.58 2-dehydro-3-deoxygalactonokinase


raffinose + H2O <=> beta-D-fructose + melibiose 2.4.1.10 levansucrase
3.2.1.26 beta-fructofuranosidase


UTP + D-tagatose_6-phosphate <=> UDP + D-tagatose_1,6-bisphosphate 2.7.1.11 6-phosphofructokinase
2.7.1.144 tagatose-6-phosphate kinase


D-tagatose_1,6-bisphosphate <=> dihydroxyacetone_phosphate + D-glyceraldehyde_3-phosphate 4.1.2.13 fructose-bisphosphate aldolase
4.1.2.40 tagatose-bisphosphate aldolase


N-acetyl-D-galactosamine + protein_Npi-phospho-L-histidine <=> N-Acetyl-D-galactosamine_6-phosphate + protein_L-histidine 2.7.1

lactose_6''-phosphate + H2O <=> D-galactopyranose_6-phosphate + D-glucose 3.2.1.85 6-phospho-beta-galactosidase

ATP + D-tagatose <=> ADP + D-tagatose_6-phosphate 2.7.1.101 tagatose kinase

galactan + H2O <=> D-galactose + galactan 3.2.1.23 beta-galactosidase

lactose + H2O <=> D-galactose + D-glucose 3.2.1.108 lactase
3.2.1.21 beta-glucosidase
3.2.1.22 alpha-galactosidase
3.2.1.23 beta-galactosidase
3.2.1.38 beta-D-fucosidase
3.2.1.62 glycosylceramidase
3.2.1.85 6-phospho-beta-galactosidase
3.2.1.B26
3.2.1.B28
3.2.1.B33
3.2.1.B34
3.7.1.4 phloretin hydrolase












D-galactose <=> D-galactose 5.1.3.3 aldose 1-epimerase

H+ + alpha-D-galactose_1-phosphate + UTP <=> UDP-galactose + diphosphate 2.7.7.10 UTP---hexose-1-phosphate uridylyltransferase
2.7.7.64 UTP-monosaccharide-1-phosphate uridylyltransferase
2.7.7.9 UTP---glucose-1-phosphate uridylyltransferase



alpha-D-glucose_1-phosphate + UTP + H+ <=> UDP-glucose + diphosphate 2.7.7.23 UDP-N-acetylglucosamine diphosphorylase
2.7.7.24 glucose-1-phosphate thymidylyltransferase
2.7.7.28 nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase
2.7.7.33 glucose-1-phosphate cytidylyltransferase
2.7.7.64 UTP-monosaccharide-1-phosphate uridylyltransferase
2.7.7.9 UTP---glucose-1-phosphate uridylyltransferase






epimelibiose + H2O <=> D-mannose + D-galactose 3.2.1.22 alpha-galactosidase

ITP + D-tagatose_6-phosphate <=> IDP + D-tagatose_1,6-bisphosphate 2.7.1.11 6-phosphofructokinase
2.7.1.144 tagatose-6-phosphate kinase


1-alpha-D-galactosyl-myo-inositol + raffinose <=> myo-inositol + stachyose 2.4.1.67 galactinol---raffinose galactosyltransferase

manninotriose + H2O <=> D-galactose + melibiose 3.2.1.22 alpha-galactosidase

raffinose + H2O <=> D-galactose + sucrose 3.2.1
3.2.1.22 alpha-galactosidase


galactitol-1-phosphate + NAD+ <=> D-tagatose_6-phosphate + NADH + H+ 1.1.1.251 galactitol-1-phosphate 5-dehydrogenase

alpha-D-glucose_6-phosphate + H2O <=> D-glucose + phosphate 3.1.3.10 glucose-1-phosphatase
3.1.3.102 FMN hydrolase
3.1.3.2 acid phosphatase
3.1.3.58 sugar-terminal-phosphatase
3.1.3.9 glucose-6-phosphatase





D-galactosamine + protein_Npi-phospho-L-histidine <=> D-galactosamine_6-phosphate + protein_L-histidine 2.7.1

D-galactono-1,4-lactone + H2O <=> D-galactonate + H+ 3.1.1.17 gluconolactonase
3.1.1.25 1,4-lactonase


D-galactose + NAD+ <=> D-galactono-1,4-lactone + NADH + H+ 1.1.1.121 aldose 1-dehydrogenase (NAD+)
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase



D-tagatose_6-phosphate + ATP <=> H+ + D-tagatose_1,6-bisphosphate + ADP 2.7.1.11 6-phosphofructokinase
2.7.1.144 tagatose-6-phosphate kinase
2.7.1.56 1-phosphofructokinase



D-galactose + ATP <=> H+ + alpha-D-galactose_1-phosphate + ADP 2.7.1.157 N-acetylgalactosamine kinase
2.7.1.162 N-acetylhexosamine 1-kinase
2.7.1.6 galactokinase



D-galactose + NAD+ <=> D-galactono-1,5-lactone + NADH + H+ 1.1.1.118 glucose 1-dehydrogenase (NAD+)
1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.121 aldose 1-dehydrogenase (NAD+)
1.1.1.122 D-threo-aldose 1-dehydrogenase
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase







melibiitol + H2O <=> D-sorbitol + D-galactose 3.2.1.22 alpha-galactosidase

UDP-glucose + alpha-D-galactose_1-phosphate <=> UDP-galactose + alpha-D-glucose_1-phosphate 2.7.7.12 UDP-glucose---hexose-1-phosphate uridylyltransferase

galactitol + NAD+ <=> D-tagatose + NADH + H+ 1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.16 galactitol 2-dehydrogenase
1.1.1.406 galactitol 2-dehydrogenase (L-tagatose-forming)



UDP-galactose <=> UDP-alpha-D-galactofuranose 5.4.99.9 UDP-galactopyranose mutase

1-alpha-D-galactosyl-myo-inositol + sucrose <=> myo-inositol + raffinose 2.4.1.82 galactinol---sucrose galactosyltransferase

D-galactosamine_6-phosphate + H2O <=> D-tagatose_6-phosphate + NH3 3.5.99
5.3.1


D-galactonate <=> H2O + 2-dehydro-3-deoxy-D-galactonate 4.2.1.140 gluconate/galactonate dehydratase
4.2.1.39 gluconate dehydratase
4.2.1.6 galactonate dehydratase



CTP + D-tagatose_6-phosphate <=> CDP + D-tagatose_1,6-bisphosphate 2.7.1.11 6-phosphofructokinase
2.7.1.144 tagatose-6-phosphate kinase


stachyose + H2O <=> manninotriose + D-fructose 3.2.1.26 beta-fructofuranosidase

protein_Npi-phospho-L-histidine + lactose <=> protein_L-histidine + Lactose_6''-phosphate 2.7.1.207 protein-Npi-phosphohistidine---lactose phosphotransferase

D-galactose + NADH <=> galactitol + NAD+ 1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.21 aldose reductase
1.1.1.255 mannitol dehydrogenase



ATP + alpha-D-glucose <=> ADP + alpha-D-glucose_6-phosphate 2.7.1.1 hexokinase
2.7.1.2 glucokinase


UDP-galactose + galactan <=> galactan + UDP 2.4.1

D-galactono-1,4-lactone + H2O <=> D-galactonate + H+ 3.1.1.17 gluconolactonase
3.1.1.25 1,4-lactonase


D-galactose + NADP+ <=> D-galactono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase








UDP-glucose <=> UDP-galactose 5.1.3.16 UDP-glucosamine 4-epimerase
5.1.3.2 UDP-glucose 4-epimerase
5.1.3.7 UDP-N-acetylglucosamine 4-epimerase



galactitol + protein_Npi-phospho-L-histidine <=> galactitol-1-phosphate + protein_L-histidine 2.7.1.200 protein-Npi-phosphohistidine---galactitol phosphotransferase

D-tagatose_6-phosphate <=> D-fructose_6-phosphate 5.1.3.40 D-tagatose 6-phosphate 4-epimerase

sucrose + H2O <=> D-fructose + D-glucose 2.4.1.10 levansucrase
2.4.1.24 1,4-alpha-glucan 6-alpha-glucosyltransferase
2.4.1.4 amylosucrase
2.4.1.9 inulosucrase
2.4.1.99 sucrose:sucrose fructosyltransferase
3.2.1.10 oligo-1,6-glucosidase
3.2.1.153 fructan beta-(2,1)-fructosidase
3.2.1.154 fructan beta-(2,6)-fructosidase
3.2.1.20 alpha-glucosidase
3.2.1.21 beta-glucosidase
3.2.1.22 alpha-galactosidase
3.2.1.26 beta-fructofuranosidase
3.2.1.28 alpha,alpha-trehalase
3.2.1.3 glucan 1,4-alpha-glucosidase
3.2.1.48 sucrose alpha-glucosidase
3.2.1.64 2,6-beta-fructan 6-levanbiohydrolase
3.2.1.65 levanase
3.2.1.7 inulinase
3.2.1.70 glucan 1,6-alpha-glucosidase
3.2.1.8 endo-1,4-beta-xylanase
3.2.1.80 fructan beta-fructosidase
3.2.1.84 glucan 1,3-alpha-glucosidase
3.2.1.B3
3.7.1.4 phloretin hydrolase
























D-galactopyranose_6-phosphate <=> D-tagatose_6-phosphate 5.3.1.26 galactose-6-phosphate isomerase

stachyose + H2O <=> raffinose + D-galactose 3.2.1.22 alpha-galactosidase
3.2.1.26 beta-fructofuranosidase


pyruvate + D-glyceraldehyde <=> 2-dehydro-3-deoxy-D-galactonate 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase
4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
4.1.2.23 3-deoxy-D-manno-octulosonate aldolase
4.1.2.51 2-dehydro-3-deoxy-D-gluconate aldolase
4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase





1-alpha-D-galactosyl-myo-inositol + H2O <=> alpha-D-galactose + myo-inositol 2.4.1.67 galactinol---raffinose galactosyltransferase
2.4.1.82 galactinol---sucrose galactosyltransferase
3.2.1.22 alpha-galactosidase



UDP-galactose + D-glucose <=> lactose + UDP + H+ 2.4.1.22 lactose synthase
2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
2.4.1.90 N-acetyllactosamine synthase



alpha-D-glucose_1-phosphate <=> alpha-D-glucose_6-phosphate 5.4.2.10 phosphoglucosamine mutase
5.4.2.2 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3 phosphoacetylglucosamine mutase
5.4.2.5 phosphoglucomutase (glucose-cofactor)
5.4.2.6 beta-phosphoglucomutase
5.4.2.8 phosphomannomutase






galactitol + NADP+ <=> D-galactose + NADPH + H+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase



H2O + N-Acetyl-D-galactosamine_6-phosphate <=> D-galactosamine_6-phosphate + acetate 3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase

D-galactose + O2 + H2O <=> D-galactonate + H2O2 1.1.3.9 galactose oxidase

UDP-galactose + myo-inositol <=> H+ + 1-alpha-D-galactosyl-myo-inositol + UDP 2.4.1.123 inositol 3-alpha-galactosyltransferase

Visualization of the pathway